Define a sign and a symptom and provide two examples of each.
What are the stages of disease and what is characteristic of each stage?
What is an opportunistic microorganism?
Provide an example of when you may be susceptible to this type of infection.
Give several examples of microbial antagonism.
How can opportunistic pathogens cause infections?
List Koch's postulates.
Explain the exceptions to Koch's postulates.
Differentiate a communicable from a noncommunicable disease.
Categorize diseases according to frequency of occurrence.
Categorize diseases according to severity.
Identify the principal portals of entry.
Define iDso and LDso.
Using examples, explain how microbes adhere to host cells.
Explain how capsules and cell wall components contribute to pathogenicity.
Compare and Contrast three things about exotoxins and endotoxins.
How do enzymes act as virulence factors? (give at least two examples)
Which are the most often used portals of exit?
Which defense system, innate or adaptive immunity, prevents entry of microbes into the body?
What relationship do TLRs have to pathogen-associated molecular patterns?
Describe the role of the skin and mucous membranes in innate immunity.
Differentiate physical from chemical factors, and list five examples of each.
Describe the role of normal microbiota in innate immunity.
Identify one physical factor and one chemical factor that prevent microbes from entering the body through skin and mucous membranes.
Identify one physical factor and one chemical factor that prevent microbes from entering or colonizing the body through the eyes, digestive tract, and respiratory tract.
Classify leukocytes, and describe the roles of granulocytes and monocytes.
Describe the different types of WBCs, and name a function for each type.
Define phagocyte.
Describe the process of phagocytosis, and include the stages of adherence and ingestion.
Identify six mechanisms of avoiding destruction by phagocytosis.
What is the role of TLRs in phagocytosis?
List the stages of inflammation.
What purposes does inflammation serve?
What causes the redness, swelling, and pain associated with inflammation?
Describe phagocyte migration. What is complement?
Describe three pathways of activating complement.
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