The largest public health experiment involved 401,974 children who were randomly assigned to two groups.

INSTRUCTIONS TO CANDIDATES

ANSWER ALL QUESTIONS

 

Problem 1: The largest public health experiment involved 401,974 children who were randomly assigned to two groups. In one group, 201,229 children were given a placebo. In the other group, 200,745 children were treated with the Salk vaccine designed to prevent polio. Among the children in the placebo group, 115 developed polio, and among the children in Salk vaccine treatment group, 33 developed polio.

Use the methods learned in this course to determine whether there is sufficient evidence to support a claim that the Salk vaccine is effective. Does it appear that the Salk vaccine is effective? Why or why not? Write a brief report summarizing your findings and include specific statistical tests and results.

 

Problem 2: With sales of Lipitor exceeding $13 billion each year, it has been the best-selling drug ever. A statistician asked Pfizer for the original data from clinical drug trials of Lipitor, but Pfizer declined to provide the data. The data shown in Table 1 below are based on results given in a Parke-Davis memo from David G. Orloff, M.D., the medical team leader in the clinical trials. The data refer to atorvastatin, and Lipitor is the trade name of atorvastatin. Low-density lipoprotein (LDL) cholesterol is considered the bad cholesterol, so a subject’s condition is generally improved if the LDL cholesterol is lowered. The changes in LDL cholesterol listed in the table are measured in mg/dL. Note that when compared to baseline values, negative values in the following data indicate that the LDL cholesterol has been lowered.

 

Attachments:

Related Questions

. The fundamental operations of create, read, update, and delete (CRUD) in either Python or Java

CS 340 Milestone One Guidelines and Rubric  Overview: For this assignment, you will implement the fundamental operations of create, read, update,

. Develop a program to emulate a purchase transaction at a retail store. This  program will have two classes, a LineItem class and a Transaction class

Retail Transaction Programming Project  Project Requirements:  Develop a program to emulate a purchase transaction at a retail store. This

. The following program contains five errors. Identify the errors and fix them

7COM1028   Secure Systems Programming   Referral Coursework: Secure

. Accepts the following from a user: Item Name Item Quantity Item Price Allows the user to create a file to store the sales receipt contents

Create a GUI program that:Accepts the following from a user:Item NameItem QuantityItem PriceAllows the user to create a file to store the sales receip

. The final project will encompass developing a web service using a software stack and implementing an industry-standard interface. Regardless of whether you choose to pursue application development goals as a pure developer or as a software engineer

CS 340 Final Project Guidelines and Rubric  Overview The final project will encompass developing a web service using a software stack and impleme